FIG. 1. Phylogenetic tree of fungal GH 3 enzymes. Scale corresponds to a genetic distance of 0.1 substitutions per position (10% difference). GenBank protein accession numbers are:
Trichoderma reesei QM9414 b-glucosidase 1 (Bgl1, Cel3A): AAA18473.1; Trichoderma reesei QM6a Cel3B: JGI protein ID 121735; Cel3C: JGI protein ID 82227; Cel3D: JGI protein ID
46816; Cel3E: JGI protein ID 76227; Cel3F: JGI protein ID 47268; Cel3G: JGI protein ID 104797; Cel3H: JGI protein ID 66832; Hypocrea virens b-N-acetylglucosaminidase (Nag3):
ACH72647.1; Aspergillus kawachii IFO4308 b-glucosidase A (BglA): BAA19913.1; Aspergillus fumigatus Af293 b-glucosidase (Bgl): EAL91070.1; Physarum polycephalum b-glucosidase 1
(BglM1): BAE43955.1; Aspergillus aculeatus F-50 b-glucosidase 1 (Bgl1): BAA10968.1; Aspergillus japonicus MU-2 b-1,4-xylosidase (XylA): BAG82824.1; Aspergillus oryzae KBN616 bxylosidase
(XylA): BAA28267.1; Talaromyces emersonii Avenacinase (Aven1): AAM94393.3; Gaeumannomyces graminis Avenacinase I (Aven1): AAB09777.1; Uromyces viciae-fabae bglucosidase
(Bgl1): CAE01320.1; Thermoascus aurantiacus IFO 9748 b-glucosidase 1 (Bgl1): AAZ95587.1; Thermoascus aurantiacus IFO 9748 b-glucosidase 2 (Bgl2): AAY33982.1;
Aspergillus niger NRRL 3135 b-glucosidase (Bgl): CBA02054.1; Kluyveromyces marxianus NBRC1777 b-glucosidase I (Bgl): ACY95404.1; Rhizomucor miehei NRRL 5282 b-glucosidase I
(Bgl1): CAP58431.2; Talaromyces emersonii b-glucosidase (Cel3A): AAL69548.3; Aspergillus oryzae b-glucosidase I (Bgl1): CAD67686.1; Saccharomycopsis fibuligera ATCC 36309 bglucosidase
1 (Bgl1): AAA34314.1; Aspergillus oryzae RIB40 b-glucosidase 1 (Bgl5): BAE57053.1; Rhizoctonia solani AG3 b-glucosidase: ABL67526.1; Kuraishia capsulata 35 M5N bglucosidase
(BglN): AAA91297.1; Camellia sinensis b-xylosidase (Bxl): ACD93208.1; Phanerochaete chrysosporium K-3 glucan b-1,3-glucosidase (Bgl): BAB85988.1. The cluster containing
BGLs with very high cellobiase activity (*) is highlighted by a gray box.