The highest 17α-OHPL level in T2D1 was 6.8 ng/ml which was lower than at the starting point of the experiment. As for T2D2, the steroid hormone followed a decreasing trend, continuously until termination of treatment. Control was low for the whole experimental period. T2D2 highest 17α-OHPL level was at Day30 which was also lower than the starting point of the experiment similar to T1D1.