Exposure
The containers for the printing colors were cleaned by
hand with pure toluene. The room was small and had poor
ventilation. The door and the window were usually kept
closed due to low winter temperatures. Exposure was determined
by personal air sampling with adsorption on charcoal
tubes, desorption with benzylic alcohol, and headspace gas
chromatography. Venous blood samples were taken immediately
before and after cleaning, and toluene was determined
by gas chromatography. Ethanol in blood samples of exposed
workers and of controls, taken before testing, was determined
enzymatically with alcohol dehydrogenase (Sigma, Germany).
None of the workers or of the controls drank alcohol before
or during the experiment. Subjects were watched during the
whole procedure. We had intended to perform the cleaning at
the beginning of the shift when blood concentrations of toluene
were low, but this was not possible in most cases due to
the working process.
ExposureThe containers for the printing colors were cleaned byhand with pure toluene. The room was small and had poorventilation. The door and the window were usually keptclosed due to low winter temperatures. Exposure was determinedby personal air sampling with adsorption on charcoaltubes, desorption with benzylic alcohol, and headspace gaschromatography. Venous blood samples were taken immediatelybefore and after cleaning, and toluene was determinedby gas chromatography. Ethanol in blood samples of exposedworkers and of controls, taken before testing, was determinedenzymatically with alcohol dehydrogenase (Sigma, Germany).None of the workers or of the controls drank alcohol beforeor during the experiment. Subjects were watched during thewhole procedure. We had intended to perform the cleaning atthe beginning of the shift when blood concentrations of toluenewere low, but this was not possible in most cases due tothe working process.
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Exposure
The containers for the printing colors were cleaned by
hand with pure toluene. The room was small and had poor
ventilation. The door and the window were usually kept
closed due to low winter temperatures. Exposure was determined
by personal air sampling with adsorption on charcoal
tubes, desorption with benzylic alcohol, and headspace gas
chromatography. Venous blood samples were taken immediately
before and after cleaning, and toluene was determined
by gas chromatography. Ethanol in blood samples of exposed
workers and of controls, taken before testing, was determined
enzymatically with alcohol dehydrogenase (Sigma, Germany).
None of the workers or of the controls drank alcohol before
or during the experiment. Subjects were watched during the
whole procedure. We had intended to perform the cleaning at
the beginning of the shift when blood concentrations of toluene
were low, but this was not possible in most cases due to
the working process.
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