Conclusion
GME was successfully encapsulated into polymeric
nanoparticles of the polymer blend of EC and MC, with
high encapsulation efficiency (98.94 ± 6.26) and loading
capacity (49.73 ± 5.89) via solvent displacement method.
The optimum condition for GME encapsulation was at 1:1
(w/w) polymer to GME, and the best wall material was
a blend of EC (250-300 cP) and MC at 1:1 weight ratio.
The water dispersible GME-loaded nanoparticles were
spherical with hydrodynamic diameter around 625.4 ±
19.6nm.
Acknowledgements
The authors thank the Royal Golden Jubilee
PhD Program (PHD0075/2550) and the Chulalongkorn
University Ratchadapiseksompot Fund for financial