Various strategies aimed at improving the T>MIC include increasing the dose, frequency of dosing, and/or infusion times (including utilizing continuous infusions) (Shea, 2009). However, utilizing a continuous infusion may be impractical as a dedicated intravenous catheter would be required for drug administration. On the other hand, prolonging the length of the infusion to 3-4 hours enhances drug exposure while allowing time for other drugs to be administered through the same intravenous catheter. This approach has the added benefit of lower daily doses than are required by other dose optimization strategies, thereby decreasing drug expenditures