This study investigated the phytochemical constituent, proximate analysis, antioxidant,antibacterial and wound healing properties of aqueous and ethanolic leaf extracts ofChromolaena odorata (L.). Results indicated the presence of saponins, phenols and tannins inaqueous and ethanolic leaf extracts. Proximate analysis indicated that the dried leaf containedash (10.5%), crude fat (10.75%), fiber (14.9%), moisture (15%), crude protein (18.37%) andcarbohydrate (30.48%). However, aqueous extract had high antioxidant and lipid peroxideinhibitory activity while ethanolic extract showed high phenolic and hydrogen peroxideinhibitory activity at 50, 100 and 250 μg/ml respectively. Furthermore, the antibacterial studiesshowed that the ethanolic extract of C. odorata inhibited the growth of S. aureus, S. typhi and E.coli at various degrees while S. aureus and S. typhi only were inhibited by the aqueous extracts.However, aqueous extract (coagulation: 15.18 ± 0.023 min; clotting 0.26 ± 0.014 min) showedsignificantly high (p<0.05) haemostatic activity than the ethanolic extract (Coagulation: 21.0 ±0.696 min; Clotting 2.03 ± 0.035 min). The result of these studies indicates that leaf extracts ofC. odorata possess antioxidant, antibacterial and haemostatic activities which explain itsfolkloric use in animal nutrition and human medicine.
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