In 1961 John Moore required from WA to develop a 0.1 ml volume flow cell, which would enable him to develop an instrument using gel columns to analyze the MW of polymers (natural and synthetic macromolecules). After experimental work by Moore, followed by negotiations between Dow and WA and additional hard work to scale up the synthesis of the polymeric gel used in the columns, the invention of the GPC was completed, becoming a major breakthrough for WA.