Nasal symptoms are common in infants. Most of the
times they are due to benign condition such as common
cold or upper respiratory tract infection (URTI). First
generation antihistamines are usually used in treating
common cold. However, its use in infants could be
associated with apparent life-threatening events, apnoea
and sudden infant death syndrome. We reported two
infants who were admitted and had desaturation after taking oral chlorpheniramine.