extract but the predominant waste product
malate could not be detected. This may indirectly imply that G.
mangostana Linn. crude extract might interrupt TCA cycle. To
investigate the possible involvement of malate production as the
possible target of action of G. mangostana Linn., further study using
selective inhibitors of TCA pathways including atovaquone, sodium
fluoroacetate, and malate quinone oxidoreductase will be investigated
in details