This study aimed to study the growth of Aspergillus niger TISTR 3013.of production the amylase Protease and xylenes by solid state fermentation (SSF) By the fermentation broth on four substrate types is soybean, coconut, coffee grounds and bran.Was cultured at 30 C with substratemoisture content 60 percent for 72 hours.The highest growth and production amylase Protease and xylanase onsoybean substrate. The enzyme amylase 162,558 unit/g dry weight Protease 5,150 unit/g dry weight and xylenes 596,223 unit/g dry weight.