Efficacy
Damage control resuscitation, including permissive hypotension, early use of blood products, more aggressive coagulation factor replacement, and MTPs, seems to have had a beneficial effect on outcomes. A study reviewing patients with MBL who were resuscitated with classical techniques within the period of 1970 to 1990 showed that they experienced very poor outcomes, with mortality ranging from 61% to 90%.
These findings improved somewhat in later studies conducted from 1990 to the 2000s, but survival was still poor, ranging from 45% to 87%.
In contrast, current mortality rates after initiation of DCR and MTPs range from 8% to 34%.
EfficacyDamage control resuscitation, including permissive hypotension, early use of blood products, more aggressive coagulation factor replacement, and MTPs, seems to have had a beneficial effect on outcomes. A study reviewing patients with MBL who were resuscitated with classical techniques within the period of 1970 to 1990 showed that they experienced very poor outcomes, with mortality ranging from 61% to 90%.These findings improved somewhat in later studies conducted from 1990 to the 2000s, but survival was still poor, ranging from 45% to 87%.In contrast, current mortality rates after initiation of DCR and MTPs range from 8% to 34%.
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