DOT was defined as a treatment strategy where “an appointed agent directly monitors people swallowing their anti-TB drugs” [17]. CB DOT was defined as DOT provided in the community by CHWs or CVs; clinic DOT was defined as DOT delivered at a fixed health clinic, usually by a government health worker.
The definitions for CHWs and CVs in this review were based on the Global Tuberculosis Report 2013 ([1], p. 35):