Results showed that in Phitsanulok Rice Research Center the input of P, K fertilizers and growing season did not significantly affected rice grain yield and nutrient uptake. Only N fertilizer increased rice yield and nutrient uptake significantly. N uptake of rice from clayey and loamy soil were 8.1 and 8.0 kg.N/rai. The rate of N at 12.4 kg.N/rai in clayey soil and 10.5 kg.N/rai in loamy soil enhanced yield production. The ratio of N:P:K uptake in clayey and loamy soil were 3.6:1:8.1 and 3.5:1:6.3. In the farmers'fields the results were the same as in the Rice Research Center, but the recovery efficiency of N was low. The suitable rate of N fertilizer was 11-12 kg.N/rai. Suitable technology for growing rice were seed rate at 20 kg./rai with two times fertilizations. The rice yield of Phitsanulok 2 and CNT89098-281-2-1-2-1 were higher than Suphanburi 1 and farmer's varities. The package of rice seed technologies were eradicating dropping rice seeds and weeds before planting and fungicides application to control dirty panicle and false smut. For land preparation, plowing land one time by rotary, and flooding 6 days before draining were practiced. After seed germination, the field was plowed and flooded 6 days again before planting. For flooded area, plowing land a time 2 weeks before the field dried, then plowing germination seed again before planting was more suitable. Different methods of land preparation did not affect the amount of weed clearly. The best fungicides for dirty panicle control were Duett and Propiconazone, and for false smut control were Amurae and Propiconazone.