ystem is characterized to employ all their modules or domains more than once during the synthesis of a single NRP, which enables the assembling of peptide chains that contain repeated sequences along the structure. An example of this mode of synthesis occurs in Fusarium scirpi during the biosynthesis of enniatin (antibiotic), which is achieved through the repeated use of two modules. Other examples of type B NRPSs are the siderophore synthetases, which only contain three A domains that catalyze the biosynthesis of ferrichrome. In type C system, the non-linear NRPSs have at least one domain conformation that deviate from (C-A-T)n-1 organization contained in linear NRPSs. Likewise, in these synthetases the module arrangement does not correspond to the