L-arginine has few reported adverse reactions. Nausea and diarrhea have been reported infrequently. Bitter taste may occur with higher doses. Due to its ability to dilate blood vessels, low blood pressure may occur. Intravenous preparations containing L-arginine hydrochloride have a high chloride content that may increase the risk for metabolic acidosis in patients with electrolyte imbalances. Low potassium and high serum urea nitrogen levels may occur in patients with kidney and/or liver impairment.