the principal psychoactive constituent of the cannabis plant, has low toxicity, the dose of THC needed to kill 50% of tested rodents is extremely high. Acute effects may include anxiety and panic, impaired attention, and memory (while intoxicated), an increased risk of psychotic symptoms, and possibly and increased risk of accidents if a person drives a motor vehicle while intoxicated. Psychotic episodes are well-documented and typically resolve within minutes or hours. There have been few reports of symptoms lasting longer.Cannabis has not been reported to cause fatal overdose.Studies have shown that cannabis use causes impairments in memory that persist beyond short-term intoxication.