In the war with
MRSA, although humans have obtained partial success,
the challenges from antibiotic-resistant Staphylococcus
aureus are still severe. Especially during recent years,
the appearance of CA-MRSA brought humans to a
novel battle field. The hard work of many laboratories
shed a light on the relevance between genetic mutations
and MRSA phenomena, such as antibiotic resistance,
virulence, and biofilms. The mutations of MRSA could
be ideal targets for sequential development of novel
antibiotics and vaccines.