Tables 6 and 7 represents the result of f2 and f1 respectively. In
distilled water at minute four similarity factor value of profiles of
pitaya and pineapple was slightly lower than minimum standard
value of 50. The values are in bold to indicate that the values are
slightly over or below the standard value. The similarity factor
value was 46.96. On the other hand, the difference factor value was
14.85; which was close to the lowest range of difference factor.
Pineapple and guava powder tablets also showed difference in
dissolution profile at time points of four and 5 min; f1 and f2 value
was 15.57 and 42.96 for minute four respectively; however the
difference factor value and similarity factor value was 12.30 and
46.46 at min five respectively. The dissolution profile exhibited the
value of f1 and f2 represents that dissolution profiles was similar to
each other at all the time points, except these time points, minute
four and minute five.
Model-independent method of dissolution profile comparison,
difference and similarity factor analysis result presented in Tables 9
and 8 accordingly in case of dissolution medium simulated saliva.
The result shows that at all-time points, the comparison value was
within range of f1 and f2 value; that it can be treated as dissolution
profiles are similar. However there was huge variation in similarity
level among the fruit powder tablet dissolution profile at same time
point.