Luteolin inhibited the growth of MDA-MB-231 cells in a dosedependent
manner after treatment for 48 h (Fig. 1). Treatment
with 35 lM luteolin for 48 h decreased the cell number compared
with a 24-h treatment. To clarify the combination effects of luteolin
and paclitaxel, a nonlethal concentration of luteolin (0–15 lM)
was used in the following investigation.