The compounds diterpenoid furans 6alpha - hydroxyvouacapan-7beta, 17beta-lactone (1), 6alpha,7beta-dihydroxyvouacapan- 17beta-oic acid (2) and methyl 6alpha,7beta-dihydroxyvouacapan-17betaoate (3) isolated from the ethanolic extract from seeds of Pterodon polygalaeflorus(P. polygalaeflorus) exhibited LC50 values of 50.08, 14.69, and 21.76 毺g /mL against fourthinstar Ae. aegypti larvae[31]. Yenesew et al[32] reported that the crude chloroform extract of Millettia dura (M. dura) showed high activity (LC50 = 3.5 毺g/ mL at 24 h) against second-instar larvae of Ae. aegypti. Larvicidal efficacy of leaf extract of Acacia ferruginea (A. ferruginea) showed LC50 values of 5 362.6 ppm against late third instar larvae of Cx. quinquefasciatus[33].