According to Cosmetic Ingredient Review, Association of Occupational and Environmental Clinics, and the U.S. National Library of Medicine, there is strong evidence that Triethanolamine is a human skin, immune system and respiratory toxicant. One or more animal studies show sense organ effects at very low doses, especially when used around the mouth, eyes and lips, and one or more in vitro tests on mammalian cells show positive mutation results. It has been shown to cause bladder and liver cancer, as well as changes in testicles. Triethanolamine can cause allergic reactions including eye problems, dryness of hair and skin, and could be toxic if absorbed into the body over a long period of time. It can cause itching, burning, scaling, hives, and blistering of skin, all symptoms which may increase with higher concentrations.