The purpose of this project was to develop Computer Assisted Instruction (CAI) Excretory System and Digestive System for enhancement learn and understand the systems of human body, episode excretory system and the digestive system for the population is junior high school students. This project was created by using Adobe Flash Professional CS6 to help the created image and movement of the characters, the lessons and the practices. The results showed that students in junior high school learned and understand lessons more easily and the quality of learning of junior high school students better and reduction documents budget.