microbead size determination
A sample of 30 microbeads was taken from each extrusion experiment and diameters of individual microbeads were measured with an accuracy of 10 um using a microscope. The average microbead diameter are standard deviations were then calculated from the measured data.
thus,BSA loaded microbeads of verying microbead radius and of two agent particle sizes were immersed in 1.2% W/V saline to eliminat the effects of osmotic pressure and the total mass fraotion relersed by diffusion only,From these experiments,The critical volumetric loadind was found to be approximately 0.40 for microbeads made with 106-75 um BSA paricles and 0.45 for microbeads made with particles of <53 um
incrases as the partiole size of the BSA in the 1.0-0.85 mm microbeads was 1.19 (10-5) cm /h and 3.94 (10-6) cm /h for particle size ranges of 106-75 um and <53 um,respectively
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