Something as simple as a urine test may be able to distinguish between aggressive and low-grade bladder cancers, allowing doctors to tailor personalised treatments, say scientists.
Researchers measured levels of a protein shed by bladder tumours in 600 patients.
They found that higher amounts of the protein, EpCAM, in the urine were associated with more aggressive cancers.
urine test
Study author Dr Douglas Ward, from the University of Birmingham, said: “This protein could be used to help doctors to decide what the best course of investigation or treatment for the patients is, and may prevent unnecessary delays.
“We’ve known for some time that the protein EpCAM is released from some tumour cells but it wasn’t clear whether it would be useful as a way to decide the best investigation and treatment for patients suspected of having bladder cancer.
“We are now planning further studies to test the benefits of urine biomarker testing to patients and the NHS.”
Each year around 10,300 bladder cancers are diagnosed in the UK and 5,000 people die from the disease.
Something as simple as a urine test may be able to distinguish between aggressive and low-grade bladder cancers, allowing doctors to tailor personalised treatments, say scientists.Researchers measured levels of a protein shed by bladder tumours in 600 patients.They found that higher amounts of the protein, EpCAM, in the urine were associated with more aggressive cancers.urine testStudy author Dr Douglas Ward, from the University of Birmingham, said: “This protein could be used to help doctors to decide what the best course of investigation or treatment for the patients is, and may prevent unnecessary delays.“We’ve known for some time that the protein EpCAM is released from some tumour cells but it wasn’t clear whether it would be useful as a way to decide the best investigation and treatment for patients suspected of having bladder cancer.“We are now planning further studies to test the benefits of urine biomarker testing to patients and the NHS.”Each year around 10,300 bladder cancers are diagnosed in the UK and 5,000 people die from the disease.
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