Abstract
Objective: The aims of this study were to determine the
most effective solvent extract of mangosteen, anti-acneinducing
bacterial activity and the amount of -mangostin,
a major active component in each mangosteen fruit rind
extract, using high-performance liquid chromatography
(HPLC). Materials and Methods: The fruit rinds of mangosteen
were extracted with hexane, dichloromethane, ethanol
and water. The extracts were tested for antibacterial activity
against bacteria that induce acne, including Propionibacterium
acnes and Staphylococcus epidermidis .