Results: Aqueous extract (1 mg/mL) of Glycyrrhiza glabra significantly inhibited the adhesion of Helicobacter
pylori to human stomach tissue.
This effectwas related to the polysaccharides isolated fromthe extract,
with one purified acidic fraction (0.25 SPB) as main active polymer.
Purified polysaccharides did not exhibit direct cytotoxic effects against Helicobacter pylori and did not influence hemagglutination.
Additionally raw polysaccharides from Glycyrrhiza glabra were shown to have strong antiadhesive effects
against Porphyromonas gingivalis.