discussion
the use of plants and plant products for wound healing has a long history. Especially in countries like India, China and Iran that there is more interest in traditional medicine, valuable information is available on using unknown plants for treating wounds (Feringa et al., 2011). However, little scientific research has been done to prove their benefits. Today, the use of various herbal extracts that have a long history of use in traditional medicine, has also been considered in accelerating skin wound healing (Bhatia et al., 2010; Li et al., 2012). Extensive studies suggest that grape seed extract has health benefits in many ways as a result of its antioxidant effect.
Grape seed extract is rich in flavonoids and the main flavonoids found in grape seed are procyanidolic oligomers (also called proanthocyanidins) which have antioxidant properties. Scientists belive phytochemicals are able to protect cells against the damaging effect of unstable oxygen and thus prevent and inhibit occurrence of disease (Bhatia et al., 2010). Proanthocyanidins are a subtype of flavonoids and their anti-oxidant properties in wound healing has been proved. Grape seed extract is a great source of proanthocyanidins, therby according to the results of this clinical trial, we can probably say that proanthocyanidins found in grape seed along with other flavonoids, can play an important part in skin wound healing process.
discussionthe use of plants and plant products for wound healing has a long history. Especially in countries like India, China and Iran that there is more interest in traditional medicine, valuable information is available on using unknown plants for treating wounds (Feringa et al., 2011). However, little scientific research has been done to prove their benefits. Today, the use of various herbal extracts that have a long history of use in traditional medicine, has also been considered in accelerating skin wound healing (Bhatia et al., 2010; Li et al., 2012). Extensive studies suggest that grape seed extract has health benefits in many ways as a result of its antioxidant effect.Grape seed extract is rich in flavonoids and the main flavonoids found in grape seed are procyanidolic oligomers (also called proanthocyanidins) which have antioxidant properties. Scientists belive phytochemicals are able to protect cells against the damaging effect of unstable oxygen and thus prevent and inhibit occurrence of disease (Bhatia et al., 2010). Proanthocyanidins are a subtype of flavonoids and their anti-oxidant properties in wound healing has been proved. Grape seed extract is a great source of proanthocyanidins, therby according to the results of this clinical trial, we can probably say that proanthocyanidins found in grape seed along with other flavonoids, can play an important part in skin wound healing process.
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