Collagen is a natural byproduct of the leather industry with lots of applications in cosmetics and skincare. It can be obtained from the wastes generated at different steps of the leather manufacturing. It is noted for its extraordinary moisture retention
capacity [1,2]. Collagen, once hydrolyzed, turns to a mixture of peptides. In order to obtain hydrolyzed collagen from tannery waste, a hydrolysis process is realized by means of acid, alkali or enzymes. In the industry, chemical and enzymatic methods are basically used to obtain protein hydrolysates. The alkaline treatment is softer than the acid one, and is more suitable to obtain industrial hydrolysates. The enzymatic hydrolysis in an alkaline environment at moderate temperatures is highly recommended because it allows control of the reaction in order to obtain products with different
functional properties. The accessibility of peptide bonds to enzymatic hydrolysis is very important because these bonds may be