In the case discussed here, at first admission, the dialysate
was clear and abdominal pain disappeared following intraperitoneal
administration of ceftazidime, which was effective
against S. paucimobilis. However, peritonitis by the same
organism recurred on the 15th day during antibiotic treatment.
In this circumstance, adding aminoglycoside or changing
antibiotics to imipenem was helpful for treatment of
peritonitis caused by S. paucimobilis [3], so we decided to use
imipenem because the patient had a urine output of more
than 1,000 mL per day. According to International Society
for Peritoneal Dialysis guidelines, antibiotics dose should be
empirically increased by 25% in patients with residual renal
function [11]. However, residual renal function was not
considered in deciding the antibiotic dose. Thus, inadequate
dosage of antibiotics might be one of the possible causes of
treatment failures in this case.