From a public health perspective, it is now timely to reevaluate
what the optimal diet is for lowering risk of CVD. On the basis of
the results of the present study, it appears that a high-MUFA, cholesterol-
lowering diet is superior to a low-fat diet such as the Step
II diet. Although the reduction in CVD risk due to a decrease in
LDL cholesterol is similar for both a high-MUFA diet and a lowfat
diet (Step II diet), a high-MUFA diet lowers triacylglycerol
and does not decrease HDL cholesterol. In contrast, a Step II diet
increases triacylglycerol and lowers HDL cholesterol, thereby
possibly negating some of the beneficial effects of reducing LDL
cholesterol. Collectively, the results of the present study as well
as evidence from epidemiologic studies provide compelling evidence
for conducting further studies to evaluate the long-term
effects of high-MUFA, cholesterol-lowering diets that include
peanuts and nuts in different population groups on both total morbidity
and mortality and that due to CVD. Currently, however, the
evidence available is sufficient to consider a high-MUFA, cholesterol-lowering diet that includes peanuts and nuts as an acceptable,
and perhaps preferable, dietary approach for most favorably
affecting CVD risk status.
We thank Juhu Kim for assistance with the statistical analysis of the data.
From a public health perspective, it is now timely to reevaluatewhat the optimal diet is for lowering risk of CVD. On the basis ofthe results of the present study, it appears that a high-MUFA, cholesterol-lowering diet is superior to a low-fat diet such as the StepII diet. Although the reduction in CVD risk due to a decrease inLDL cholesterol is similar for both a high-MUFA diet and a lowfatdiet (Step II diet), a high-MUFA diet lowers triacylglyceroland does not decrease HDL cholesterol. In contrast, a Step II dietincreases triacylglycerol and lowers HDL cholesterol, therebypossibly negating some of the beneficial effects of reducing LDLcholesterol. Collectively, the results of the present study as wellas evidence from epidemiologic studies provide compelling evidencefor conducting further studies to evaluate the long-termeffects of high-MUFA, cholesterol-lowering diets that includepeanuts and nuts in different population groups on both total morbidityand mortality and that due to CVD. Currently, however, theevidence available is sufficient to consider a high-MUFA, cholesterol-lowering diet that includes peanuts and nuts as an acceptable,and perhaps preferable, dietary approach for most favorablyaffecting CVD risk status.We thank Juhu Kim for assistance with the statistical analysis of the data.
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