A set of 5 criteria to assess the proposed 205 research questions
was agreed on.
The scoring criteria were based on CHNRI methodology
[8–12]
i. Likelihood of answering the question in an ethical way
ii. Likelihood of efficacy
iii. Likelihood of deliverability and acceptability
iv. Likelihood for an important disease burden reduction
v. Predicted effect on equity
During the preliminary meeting, 14 experts invited from the
larger pool of responders completed their scoring to test the
methodology. The remaining experts were asked independently
to answer a set of questions via an online survey on
all the chosen criteria for all listed research options. Scores
from a total of 91 experts were received.