Archaeological excavations show that the Lawa tribe lived in the area some 1,600 years ago. The first official town was founded in 1793.
During the thesaphiban reforms in the reign of King Rama V at the beginning of the 20th century, the town (mueang) was upgraded to a province. In 1932, when the country experienced the great economic depression, the province was demoted and included as a district into Maha Sarakham Province to reduce the financial burden on the country,[2] Kalasin was dependent on Maha Sarakham for 16 years. After the great recession and WWII, it once again became a province in 1947.[3]