With the exception of a small, but significant, increase in totalcholesterol:HDL cholesterol (MD 0.09; 95% CI 0.02, 0.16; four trials with 326 participants; I2 0%)(Annex 9: Fig. A9.30), no significant effects were observed for any blood lipid measure in RCTsor prospective cohort studies (Table 5; Annex 9: Fig. A9.31–A9.34), including LDL cholesterol ortriglycerides (Fig. 23 and 24).