Phytochemical investigations of the neotropical ginger species Renealmia alpinia and Renealmia cernua led to the isolation of two hitherto unknown diarylheptanoids, named renealpin (1) and renecernin (2). Furthermore, five known diarylheptanoids (3–7), one chalcone (9), two flavonoids (10, 11) and [2]-gingerol (8) were isolated. The organ specific accumulation patterns and chemosystematic significance of these compounds are discussed.