Enteropathogenic (EPEC) strains are classi ed as either typical or atypical, and are described as attaching and effacing pathogens due to their ability to form distinctive lesions on the surfaces of intestinal epithelial cells. Typical EPEC strains have been recognized as important agents of diarrhea in developing countries while atypical strains have been commonly isolated in developed countries (Santona et al. 2013). These two subgroups of EPEC are differentiated based on the presence or absence of a bundle forming pili gene (bfpA) (Santona et al. 2013). Clinical
presentation of EPEC infection includes watery diarrhea often accompanied by fever, vomiting, and dehydration in infants. EAEC causes acute or persistent diarrhea among infants, and has been responsible for large outbreaks in Europe, the United Kingdom, Switzerland, and Japan as well as in developing countries