Laboratory confirmation of dengue infection is crucial as the broad spectrum of clinical presentations, ranging from mild febrile illness to several severe syndromes, can make accurate diagnosis difficult. Early laboratory confirmation of the clinical diagnosis can be valuable because some patients quickly progress from mild to severe disease and sometimes death.Dengue can be diagnosed through isolation of the virus, by serological tests or by molecular methods. Currently, virus isolation and serotype identification, nucleic acid detection,antigen detection, various antibody tests (IgM ELISA, IgM Rapid test and IgG ELISA by paired sera, haemagglutination inhibition or neutralisation test) are available (table 2).