Actinobacteria are a group of ubiquitous Gram-positive bacteria with a percentage of guanine–cytosine higher than 55%, and most of them produce mycelia. Because of their ability to provide a broad range of bioactive compounds, these microorganisms have attracted much interest. Members of this group, in particular those belonging to the genus Streptomyces, are considered as the most important producers of bioactive molecules. Therefore, Streptomyces have been thoroughly investigated with
respect to their effects against pathogenic strains and have led to the discovery of a large number of novel active compounds of considerable value (Solecka et al. 2012). However, the present context of both a decline in the dis- covery of new antibiotics and an increase in drug-resistant pathogens makes the screening for new antibiotic producing Streptomyces essential.