However, the results reported herein demonstrate that the butanol extract obtained from Capsicum baccatum fruit, which
did not show detectable amounts of capsaicin (Fig. 2A), was the most active extract in the experimental model of pleurisy in mice.Moreover, the sample richest in capsaicin, the dichloromethane extract of the fruit showed no anti-inflammatory effect. Thus, thereare other compounds present in the Capsicum baccatum fruit that have potent anti-inflammatory activity in addition to capsaicinoids.