Remineralisation properties.
The research performed by Professor Sauro and his team showed that the remineralisation properties of bioactive ion-releasing resin-based materials can be potentiated when they are employed in combination with biomimetic phosphoproteins' analogues of dentine mineralization such as Zoledronic acid. It is well known that resin-hybridized dentin can be affected by the proteolytic action of host-derived matrix metalloproteinases present within the dentine matrix, also in the absence of bacterial enzymes.
However, collagen degradation within incompletely infiltrated hybrid layers may be prevented by biomimetic remineralization of the denuded collagen fibrils within the resin-dentine bonding interface.
The research team which produced this scientific data was leaded by Professor Sauro in collaboration with professor Arzu Tezvergil-Mutluay and Dr. Roda Seseogullari Dirihan from the University of Turku (Finland); Dr. Victor Feitosa, from the Federal University of Ceará (Brazil); Professors Franklin Tay and David Pashley, from Georgia Health Sciences University (United States); Professor Tim Watson from King's College London Dental Institute at Guy's Hospital (United Kingdom).
Research line.
Salvatore Sauro, Professor of Biomaterials and Minimally Invasive Dentistry at University CEU Cardenal Herrera (CEU-UCH) in Valencia (Spain), has been working on an impressive research program where the main objective is the development of bioactive restorative and/or preventive materials with potential regenerative properties for dental tissues.
Professor Sauro has more than 15 years of experience in dental adhesion, preventive and biomaterials research with more than 60 scientific articles in international peer-review journals, 1 international patent and 1 Brazilian patent. He has a wide international collaboration network with several centers of research and dental school around the world. His international and strong scientific reputation has allowed him to become visiting professor at the Federal University of Ceará, Brazil, where he is leading a research project for the development of innovative restorative materials with bioactive and anti-bacterial properties.
Cooperation with international universities and schools of Dentistry
Professor Sauro has recently published two further research papers. The first one accepted in the Journal of Biomaterials Science is about the remineralisation evoked by polycarboxylated microfillers incorporated into resin-based dental adhesives. This was developed in collaboration with researchers from the universities of Wuhan and Shanghai (China), the Vancouver campus of the University of British Columbia (Canada), and the London Dental Institute at Guy's Hospital (United Kingdom).
The second recent paper, published in the International Journal of Adhesion & Adhesives, focused on the assessment of the adhesion ability of innovative bioactive root canal resin-cements to the root dentin. This research was carried out in collaboration with Professor Arlinda Luzi, at CEU-UCH, and researchers from the Universities of Roma Tor Vergata, Federal University of Ceará (Brazil) and the London Guy's Hospital (United Kingdom).