IR was identified by HOMA-IR , obtained by the formula : HOMA-IR = fasting insulin (mU/L) X fasting glucose (mmol/L)/22.5 . The receiver operating characteristic curve (ROC) was used for the identification of IR. To determine the gold standard for implementing the ROC curve,with subsequent identification of the value of highest IR sensitivity and specificity in this sample reference value in the literature healthy adult subject were used,thus obtaining a value >4.0 as cutoff point.