Several risk factors have been identified regard- ing the development of chronic pain [18,19]. Among the strongest predictors is emotional dis- tress, including depression [20]. Depression is more frequent in patients with musculoskeletal pain, and is reported at higher levels in the chronic compared with the acute situation [21] and in the presence of generalized compared with localized pain [22]. More widespread pain distribution is also associated to impaired function and disability [16], which need to be taken into consideration when investigating the relationship to neuropathic symptoms.