General
In human interventions, doses up to 50mg have been used in interventions with no significant reported side-effects[34][29] and doses in the range of 25-100mg in open-label studies lasting up to 6 months have failed to show any relevant toxic effects.[26][27]
Currently no significant side-effects associated with supplemental Pueraria Mirifica at the standard supplemental dosages
This does not mean Pueraria Mirifica is wholly safe, as its potency and mechanisms suggest that it carries the same risks and benefits as estrogen replacement therapy (these are currently not studied as it pertains to Pueraria Mirifica)