A total of 397 patients were evaluated, including 131 (33.0%)
and 266 (67.0%) diagnosed with HIV between 1996 and 2004 and
2005–2012, respectively (Table 1). Baseline characteristics were no
different between groups and themajority of patients were enlisted
males with a median age of 28 years at HIV diagnosis. Patients were
most commonly Caucasian (44.2%) or African American (43.4%). A
total of 41 (10.3%) patients had STI diagnoses prior to HIV diagnosis.
The median CD4 count (cells/uL) at HIV diagnosis was 543
(interquartile range [IQR] 399–694) and 510 (IQR 378–665) for the
1996–2004 and 2005–2012 groups, respectively (P = 0.39).
HSV-2 seroprevalence at HIV diagnosis decreased from the
period of 1996–2004 to 2005–2012 (P < 0.01), while HSV-1 seroprevalence
was stable (Table 2). Odds of HSV-2 seropositivity was
significantly greater for non-Caucasians (odds ratio [OR] 2.19, 95%
CI 1.33–3.60) and for HIV diagnosis between 1996 and 2004 (OR
2.06, 95% CI 1.29–3.27), with a trend observed for those age >30
years at HIV diagnosis (1.73, 95% CI 0.94–3.18; Table 3). A total of 81
(20.4%) patients developed STIs by ICD-9 codes after HIV diagnosis,