4.1. ConM binds to active and inactive IAA forms
IAA was found near the site previously shown to bind to alpha-aminobutyric acid (ABU) in the Canavalia gladiata lectin (CGL) [36], but in a lateral position relative to the canonical dimer. According to the structure, IAA would be released upon dissociation of the tetramer into dimers. Previous studies have shown a pH-dependent equilibrium between the dimer and tetramer: under acidic conditions (∼pH 5.5), the dimeric form predominates, whereas under neutral conditions (pH ∼7.5), the tetrameric form predominates [56] and [57].