Statistical Analysis
Only the Caucasian participants from the DREW trial, with complete weight measurements
(n=234), were included in the present analyses, since rs8050136 has previously been shown
to be associated with obesity predominantly in Caucasian populations (8). Linear mixed models
(PROC MIXED), using unstructured covariance, were used to determine statistical
significance with genotype by exercise interactions tested. All data are presented as least-square means with standard error (SE); statistical significance was set at an alpha level of 0.05
and all analyses were performed using SAS (version 9.2).