A total of 2,110 patients (72% of the study population )had organ failure at some point during their ICU stay. Patients who exhibited an impovement in organ function the first 24 hours after admission to the ICU had lower ICU and hospital mortality rates compared with thorse who had unchanged or increased SOFA scores(12.4 and 18.4% versus 19.6 and 24.5%,P<0.05,pairwise). Aspected, organ failure was more common in sepsis than in nonsepsis patients. In patients with multiorgan failure,motality rates were similar regardless of the presence of sepsis. Irrespective of the presence of sepsis, delta SOFA scores over the first 4 days in the ICU were higher in non survivors than in survivors and decreased significant over time in surviors
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