A standardized extract from Tinospora known as Tinofend has been studied clinically. One study in 75 patients with allergic rhinitis (hay fever) showed statistically significant reduction of symptoms compared to placebo.[7] An independent review of this study concluded that "significant intergroup differences were seen in all symptoms", although studies in larger populations may support this finding.[8] A combination of T. cordifolia extract and turmeric extract is effective in reducing the hepatotoxicity which is induced by the combination of isoniazid, rifampicin, pyrazinamide and ethambutol for treating tuberculosis