TRIzol® Reagent is a ready-to-use reagent, designed to isolate high quality total RNA (as well as DNA and proteins) from cell and
tissue samples of human, animal, plant, yeast, or bacterial origin, within one hour. TRIzol® Reagent is a monophasic solution of
phenol, guanidine isothiocyanate, and other proprietary components which facilitate the isolation of a variety of RNA species of
large or small molecular size. TRIzol® Reagent maintains the integrity of the RNA due to highly effective inhibition of RNase
activity while disrupting cells and dissolving cell components during sample homogenization. TRIzol® Reagent allows for
simultaneous processing of a large number of samples, and is an improvement to the single-step RNA isolation method developed
by Chomcynski and Sacchi (Chomczynski & Sacchi, 1987).