Should a laboratory not usually use a test which is sensitive to HIV-2, but the person testing has lived in a country where HIV-2 is common (or has a sexual partner from one of those countries), it is important to use a different test for this person. Moreover, if a person has clinical signs of HIV infection (e.g. recurrent opportunistic infections) but does not test positive to a test which is sensitive only to HIV-1, then testing specifically for HIV-2 would be appropriate.