The leaves are reputed to have pain-killing properties and slightly narcotic ones. The fruit is a purgative and phlegmatic, and a decoction of the roots is given for asthma and as a general tonic. The leaves are made into poultices for piles. The juice from the leaves is used in some traditional medicine systems for skin problems and a decoction of the leaves is given for gastrointestinal problems. It is said that the roots, boiled with sour milk and grain porridge is used for syphilis.
Solanum mammosum has much the same properties as other plants in the Solanaceae family, and more research is being carried out to see how they can benefit us.